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In a study by Hostynek et al., three different layers of skin from human cadavers (isolated stratum corneum, isolated epidermis, and dermatomed skin) were employed to portray the penetration of GHKCu as a potential anti-inflammatory agent [69]

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Given these data and the fact that the literature about pregnancy in clEDS is sparse, we advise gynecological follow-up during pregnancy and specialist delivery with careful handling as recommended in the literature

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