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These findings indicate that intensified monitoring should be implemented at the initiation of immunotherapy, while continued vigilance is also warranted during long-term treatment, particularly in the context of sustained immune activation and the potential additive effects of prior or concurrent chemoradiotherapyrelated radiation lung injury

29 , 21542163.e5 (2019)

Thus, iRGD increases the tissue penetration of drugs regardless of whether it is conjugated to or coadministered with the drug 16,17,18

A systematic review showed that the TfR to ferritin ratio was negatively related to the risk of T2DM and that plasma transferrin may be related to diabetes development directly or indirectly [24]