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Quick Picks Best Air Purifiers for Cigarette Smoke Austin Air HealthMate best overall for households where someone smokes indoors daily IQAir HealthPro Plus best premium pick for large rooms and maximum particle + gas filtration Levoit Core 600S best for large open-plan spaces with smart home integration Winix 5510 best mid-range pick for occasional or light smoke exposure Coway Airmega AP-1512HH (Coway Mighty) best for small rooms and apartment dwellers dealing with drifting smoke For more on sizing a purifier to a large open floor plan specifically, see our best air purifier for large rooms guide