doi: 10.1136/bmj.c869 Summary Keywords obesity, GLP-1, GLP-1 receptor analog, exenatide, pediatrics, glycemic control, GLP-1 receptor agonist, treatment Citation Stenlid R, Cerenius SY, Wen Q, Aydin BK, Manell H, Chowdhury A, Kristinsson H, Ciba I, Gjessing ES, Mrwald K, Gomahr J, Heu V, Weghuber D, Forslund A and Bergsten P (2023) Adolescents with obesity treated with exenatide maintain endogenous GLP-1, reduce DPP-4, and improve glycemic control
doi: 10.1210/en.2008-0828 73 KerrBDFlattPRGaultVA
Duration of Treatment GLP-1 medications are typically continued long-term: Ongoing treatment: Benefits persist with continued treatment but diminish if the medication is stopped
This is largely owing to trial variability, incorporation of trials with smaller scale trials reporting on MI rates [44, 47, 48, 51, 52, 59], the heterogeneity of the study population, and incorporation of zero total event trials in the current analysis [47, 48, 51, 52, 59]