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Here are some of the most common contraindications for semaglutide for weight loss: History of thyroid cancer: Semaglutide has been shown to cause thyroid tumors in animals, and therefore, it is not recommended for individuals with a history of thyroid cancer or those with a family history of medullary thyroid carcinoma (MTC)

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RD-MI: Retrieved Drop-outs Multiple Imputation A reduction in body weight was observed with WEGOVY irrespective of age, sex, race, ethnicity, BMI at baseline, body weight (kg) at baseline, and level of renal function impairment